In one corner of the ring, you have the guys who are insistent that nothing can make a difference in the USB audio chain - they argue that an external hard drive runs fine and transmit data without error - no fancy USB cable or anything else is needed.
In the other corner, you have the guys sitting with every single box, tweak and power supply known to man. Stock USB cable from computer to DAC ? Surely you jest. Instead, you have aftermarket USB cables (some of which cost more than your typical computer), devices designed to clean up the data line and power line, regenerate the signal, offer galvanic isolation. Add to that mix, high quality low ripple power supplies designed to power all of that. Not content to use a single device ? Heck, you have the daisy chain users. One of the threads on another forum on the popular Uptone Regen has a discussion on using two Regens in series, and which version should be used where.
Care to share what you use and what difference it made ?